Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Rattus Norvegicus (rat) Homo Sapiens (human)
TISSUE(S): Spleen, Permanent Cell Line Cell
DISEASE(S): Ankylosis
SUBMITTER: Dganit Melamed Kadosh
LAB HEAD: Arie Admon
PROVIDER: PXD007756 | Pride | 2018-04-10
REPOSITORIES: Pride
Yair-Sabag Shira S Tedeschi Valentina V Vitulano Carolina C Barnea Eilon E Glaser Fabian F Melamed Kadosh Dganit D Taurog Joel D JD Fiorillo Maria Teresa MT Sorrentino Rosa R Admon Arie A
Proteomics 20180313 9
The HLA-B*27 peptidome has drawn significant attention due to the genetic association between some of the HLA-B*27 alleles and the inflammatory rheumatic disease ankylosing spondylitis (AS), for which a comprehensive biological explanation is still lacking. This study aims to expand the known limits of the HLA-B*27 peptidome to facilitate selection and testing of new peptides, possibly involved in the disease. The HLA peptidomes of HeLa and C1R cell lines stably transfected with the AS-associate ...[more]