Cytoplasmic Proteomics for Temozolomide Resistance in Glioblastoma

ABSTRACT: TMZ resistance is one of the main reasons why treatment of glioblastoma (GBM) fails. In order to investigate the underlying mechanism associated with TMZ resistance, we conducted a cytoplasmic proteome research of U87 cells treated with TMZ for 1 week. A total of 162 DEPs including 66 up-regulated proteins and 96 down-regulated proteins were identified.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture

DISEASE(S): Brain Glioblastoma Multiforme

SUBMITTER: Yawei Liu  

LAB HEAD: Yawei, Liu

PROVIDER: PXD007759 | Pride | 2018-10-23

REPOSITORIES: Pride