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Sex determination of human remains from peptides in tooth enamel

ABSTRACT: Biological sex determination of human remains by means of a minimally destructive surface acid etch of tooth enamel and subsequent identification of sex chromosome linked isoforms of Amelogenin– an enamel-forming protein - by nano-liquid chromatography mass spectrometry(nanoLC-MS).

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Tooth Enamel

SUBMITTER: Nicolas Stewart

LAB HEAD: Nicolas Andre Stewart

PROVIDER: PXD007856 | Pride | 2017-12-12

REPOSITORIES: Pride

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Sex determination of human remains from peptides in tooth enamel.

Stewart Nicolas Andre NA Gerlach Raquel Fernanda RF Gowland Rebecca L RL Gron Kurt J KJ Montgomery Janet J

Proceedings of the National Academy of Sciences of the United States of America 20171211 52

The assignment of biological sex to archaeological human skeletons is a fundamental requirement for the reconstruction of the human past. It is conventionally and routinely performed on adults using metric analysis and morphological traits arising from postpubertal sexual dimorphism. A maximum accuracy of ∼95% is possible if both the cranium and os coxae are present and intact, but this is seldom achievable for all skeletons. Furthermore, for infants and juveniles, there are no reliable morpholo ...[more]

PMID: 29229823

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