Fibroblast activation - CTGF/VEGFA-activated fibroblasts promote tumor migration through micro-environmental modulation

ABSTRACT: The tumour secretome contains proteinaceous factors that could potentially cause activation of neighbouring fibroblasts via contact-independent processes. In this project, we aim to identify such paracrine activators of tumour origin and elucidate the functional impact of activation on fibroblasts and the tumour metastatic process.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Fibroblast

DISEASE(S): Breast Cancer

SUBMITTER: wei wu  

LAB HEAD: Albert JR Heck

PROVIDER: PXD007898 | Pride | 2018-07-23

REPOSITORIES: Pride