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Lipid rafts can form in the inner and outer membranes of Borrelia burgdorferi and have different properties and associated proteins.

ABSTRACT: Analyze the biochemically-defined proteome of lipid rafts from the inner membrane and outer membrane of Borrelia burgdorferi.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Caenorhabditis Elegans

SUBMITTER: Alvaro Toledo

LAB HEAD: Alvaro M. Toledo

PROVIDER: PXD007904 | Pride | 2018-01-30

REPOSITORIES: Pride

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Lipid rafts can form in the inner and outer membranes of Borrelia burgdorferi and have different properties and associated proteins.

Toledo Alvaro A Huang Zhen Z Coleman James L JL London Erwin E Benach Jorge L JL

Molecular microbiology 20180215 1

Lipid rafts are microdomains present in the membrane of eukaryotic organisms and bacterial pathogens. They are characterized by having tightly packed lipids and a subset of specific proteins. Lipid rafts are associated with a variety of important biological processes including signaling and lateral sorting of proteins. To determine whether lipid rafts exist in the inner membrane of Borrelia burgdorferi, we separated the inner and outer membranes and analyzed the lipid constituents present in eac ...[more]

PMID: 29377398

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