Differential kinobeads selectivity profiling
Ontology highlight
ABSTRACT: The goal of this project was to use differential kinobeads profiling for the discrimination of reversible and irreversible kinase targets of different covalent kinase inhibitors. For this, differences in target engagement measured in a lysate- and a cell-based kinobeads assay were compared in a kinome-wide scale.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell Of Alveolus Of Lung, B Cell
SUBMITTER:
Maria Faelth Savitski
LAB HEAD: Marcus Bantscheff
PROVIDER: PXD007920 | Pride | 2017-10-13
REPOSITORIES: Pride
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