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Deep Multilayer Tissue Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression

ABSTRACT: The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.

INSTRUMENT(S): LTQ Orbitrap Elite, Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain

DISEASE(S): Alzheimer's Disease

SUBMITTER: xusheng wang

LAB HEAD: Junmin Peng

PROVIDER: PXD007974 | Pride | 2019-11-11

REPOSITORIES: Pride

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