Proteomics

Dataset Information

44

A Comprehensive Transcriptomic and Proteomic Analysis of Hydra Head Regeneration


ABSTRACT: The cnidarian freshwater polyp Hydra sp. exhibits an unparalleled regeneration capacity in the animal kingdom. Using an integrative transcriptomic and stable isotope labeling by amino acids in cell culture proteomic/phosphoproteomic approach, we studied stem cell-based regeneration in Hydra polyps.

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Hydra vulgaris  

TISSUE(S): Whole Body

DISEASE(S): Not Available

SUBMITTER: Hendrik Petersen  

LAB HEAD: Thomas Wilhelm Holstein

PROVIDER: PXD008039 | Pride | 2017-10-27

REPOSITORIES: pride

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Publications


The cnidarian freshwater polyp Hydra sp. exhibits an unparalleled regeneration capacity in the animal kingdom. Using an integrative transcriptomic and stable isotope labeling by amino acids in cell culture proteomic/phosphoproteomic approach, we studied stem cell-based regeneration in Hydra polyps. As major contributors to head regeneration, we identified diverse signaling pathways adopted for the regeneration response as well as enriched novel genes. Our global analysis reveals two distinct mol  ...[more]

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