Comparison of Nuclear Matrix and Mitotic Chromosome Scaffold proteins in Drosophila S2 cells – Transmission of hallmarks of nuclear organization through mitosis
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ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Drosophila Melanogaster (fruit Fly)
TISSUE(S): Cell Culture, Early Embryonic Cell
SUBMITTER: 
RAHUL SUREKA
LAB HEAD: Rakesh Kumar Mishra
PROVIDER: PXD008404 | Pride | 2018-07-17
REPOSITORIES: Pride
Publications
Comparison of Nuclear Matrix and Mitotic Chromosome Scaffold Proteins in <i>Drosophila</i> S2 Cells-Transmission of Hallmarks of Nuclear Organization Through Mitosis.
Sureka Rahul R Wadhwa Rashi R Thakur Suman S SS Pathak Rashmi U RU Mishra Rakesh K RK
Molecular & cellular proteomics : MCP 20180710 10
Chromatin condenses several folds to form mitotic chromosomes during cell division and decondenses post-mitotically to reoccupy their nuclear territory and regain their specific transcriptional profile in a precisely lineage specific manner. This necessitates that the features of nuclear architecture and DNA topology persist through mitosis. We compared the proteome of nuclease and high salt resistant fraction of interphase nucleus known as nuclear matrix (NuMat) and an equivalent biochemical fr ...[more]
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