Mammalian proteome changes during oxidative stress and stress of the endoplasmic reticulum

ABSTRACT: Stress due to protein misfolding in the endoplasmic reticulum affects transcription and translation, RNA and protein degradation. By integrating several large-scale datasets, we quantified transcription, translation, RNA-protein binding events, and protein levels for several thousands of genes in HeLa cells. Here, we deposit the TMT-based, quantitative proteomics data consisting of two replicates with four measured time points collected for two stress treatments, i.e. tunicamycin and hydrogen peroxide.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hela Cell

SUBMITTER: Christine Vogel  

LAB HEAD: Christine Vogel

PROVIDER: PXD008575 | Pride | 2018-10-11

REPOSITORIES: Pride