Proteogenomic Analysis of Medulloblastoma
Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA430801PRJNA430807PRJNA430808GSE109403
INSTRUMENT(S): LTQ Orbitrap XL
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Medulloblastoma Cell
DISEASE(S): Childhood Medulloblastoma
SUBMITTER: 
Samuel Rivero-Hinojosa
LAB HEAD: Brian R. Rood
PROVIDER: PXD008750 | Pride | 2018-06-10
REPOSITORIES: Pride
Publications
Proteomic analysis of Medulloblastoma reveals functional biology with translational potential.
Rivero-Hinojosa Samuel S Lau Ling San LS Stampar Mojca M Staal Jerome J Zhang Huizhen H Gordish-Dressman Heather H Northcott Paul A PA Pfister Stefan M SM Taylor Michael D MD Brown Kristy J KJ Rood Brian R BR
Acta neuropathologica communications 20180607 1
Genomic characterization has begun to redefine diagnostic classifications of cancers. However, it remains a challenge to infer disease phenotypes from genomic alterations alone. To help realize the promise of genomics, we have performed a quantitative proteomics investigation using Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and 41 tissue samples spanning the 4 genomically based subgroups of medulloblastoma and control cerebellum. We have identified and quantitated thousands o ...[more]
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