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Pneumococcal surface tryptic digestion

ABSTRACT: Surface digestion of living pneumococcal cells grown in different media that attempt to simulate different infection models (for example, in culture media containing the soluble secreted fraction orignated by the growth of macrophages and epithelial cells)

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Streptococcus Pneumoniae

TISSUE(S): Prokaryotic Cell

DISEASE(S): Pleural Empyema

SUBMITTER: Alfonso Olaya Abril

LAB HEAD: Manuel José Rodríguez Ortega

PROVIDER: PXD008885 | Pride | 2022-02-15

REPOSITORIES: Pride

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Publications

Approaching In Vivo Models of Pneumococcus-Host Interaction: Insights into Surface Proteins, Capsule Production, and Extracellular Vesicles.

Olaya-Abril Alfonso A González-Reyes José A JA Rodríguez-Ortega Manuel J MJ

Pathogens (Basel, Switzerland) 20210828 9

Infections caused by the Gram-positive bacterium <i>Streptococcus pneumoniae</i> have become a major health problem worldwide because of their high morbidity and mortality rates, especially in developing countries. This microorganism colonizes the human upper respiratory tract and becomes pathogenic under certain circumstances, which are not well known. In the interaction with the host, bacterial surface structures and proteins play major roles. To gain knowledge into gradual changes and adaptiv ...[more]

PMID: 34578131

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