Proteomics

Dataset Information

0

Chicken liver cells under mycotoxin treatment with iTRAQ sequencing


ABSTRACT: We used iTRAQ technology to sequence the proteome for chicken liver cells under mycotoxin treatment.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Gallus gallus  

TISSUE(S): Liver

DISEASE(S): Not Available

SUBMITTER: Yu Sun  

LAB HEAD: yu sun

PROVIDER: PXD008961 | Pride | 2019-07-10

REPOSITORIES: Pride

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Publications

Variable protein homeostasis in housekeeping and non-housekeeping pathways under mycotoxins stress.

Sun Yu Y   Wen Jikai J   Chen Ruohong R   Deng Yiqun Y  

Scientific reports 20190524 1


Transcript levels are the primary factor determining protein levels, but for the majority of genes, fold changes in transcript levels are larger than the corresponding changes in protein levels, a phenomenon that is termed "protein homeostasis". However, this phenomenon is not well characterized in the context of environmental changes. In this study, we sequenced the entire transcriptome and proteome of chicken primary hepatocytes administered three mycotoxin treatments Aflatoxin B1 (AFB1), Ocho  ...[more]

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