Dynamic changes in the protein localization in the nuclear environment in pancreatic β-cell after brief glucose stimulation

ABSTRACT: We focus on the characterization of proteins in the nuclear environment of β-cells after brief, high glucose-stimulation. We compared purified nuclei derived from β-cells stimulated with 17mM glucose for 0, 2, and 5 minutes using quantitative proteomics, a time frame that most likely does not result in translation of new protein in the cell.

INSTRUMENT(S):

ORGANISM(S): Rattus Norvegicus (rat) Mus Musculus (mouse)

TISSUE(S): Type B Pancreatic Cell, Cell Culture

SUBMITTER: Taewook Kang  

LAB HEAD: Martin R. Larsen

PROVIDER: PXD008988 | Pride | 2018-03-12

REPOSITORIES: Pride