Dissecting the malaria interactome

ABSTRACT: To identify malaria protein interactions systematically we combined blue native polyacrylamide electrophoresis fractionation with quantitative mass spectrometry and machine learning. Our integrative approach identified over twenty thousand protein interactions in Plasmodium schizonts, organized into 600 complexes, the majority of which are novel, and generated a high-confidence Plasmodium protein interaction network.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

DISEASE(S): Plasmodium Falciparum Malaria

SUBMITTER: James Wright  

LAB HEAD: Jyoti Choudhary

PROVIDER: PXD009039 | Pride | 2019-08-06

REPOSITORIES: Pride