GAGfinder: glycosaminoglycan MS/MS fragment peak finding and elemental composition assignment

ABSTRACT: This study shows the efficacy of a new tandem mass spectrometry peak finding software, GAGfinder. GAGfinder works by iterating through all potential fragments of a given precursor composition and comparing a theoretical isotopic distribution to the peak heights found in a tandem mass spectrum. We used ten synthetic heparan sulfate oligosaccharide to test the effectiveness of the method and compare GAGfinder's performance to that of an averagine-based algorithm.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: John Hogan  

LAB HEAD: Joseph Zaia

PROVIDER: PXD009101 | Pride | 2018-04-09

REPOSITORIES: Pride