Proteomics

Dataset Information

0

LIver Glycogen SWATH Proteomics


ABSTRACT: Identification and relative quantification of proteins associated with mammalian liver glycogen.

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Rattus Norvegicus (rat) Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Liver

SUBMITTER: Benjamin Schulz  

LAB HEAD: Benjamin Luke Schulz

PROVIDER: PXD009140 | Pride | 2018-07-23

REPOSITORIES: Pride

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Publications

Proteomic Investigation of the Binding Agent between Liver Glycogen β Particles.

Tan Xinle X   Sullivan Mitchell A MA   Nada Sharif S SS   Deng Bin B   Schulz Benjamin L BL   Gilbert Robert G RG  

ACS omega 20180402 4


Glycogen is a highly branched glucose polymer which plays an important role in glucose storage and the maintenance of blood sugar homeostasis. The dimeric protein glycogenin can self-glucosylate to act as a primer for glycogen synthesis, eventually resulting in small (∼20 nm diameter) glycogen β particles with a dimer of glycogenin at their core. In the liver, glycogen is also found in the form of α particles: large bound composites of many β particles. Here, we provide evidence using qualitativ  ...[more]

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