The endosomal proteome of LAMTOR2-deficient primary macrophages

ABSTRACT: A quantitative iTRAQ-based organelle proteomics analysis of endosomes derived from LAMTOR2-deficient macrophages has been performed. Primary macrophages were derived from bone marrow of conditional knockout mice carrying a specific deletion of LAMTOR2 in the monocyte/macrophage cell lineage. The combined proteomics and transcriptomics data indicated a function of LAMTOR2 in lipid metabolism.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Bone Marrow, Macrophage

SUBMITTER: Taras Stasyk  

LAB HEAD: Lukas A. Huber

PROVIDER: PXD009148 | Pride | 2019-08-26

REPOSITORIES: Pride