Dataset Information
Extracellular vesicles from Nippostrongylus brasiliensis
Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Nippostrongylus Brasiliensis
SUBMITTER: 
Ramon Eichenberger
LAB HEAD: Alex Loukas
PROVIDER: PXD009165 | Pride | 2018-10-19
REPOSITORIES: Pride
Publications
Hookworm Secreted Extracellular Vesicles Interact With Host Cells and Prevent Inducible Colitis in Mice.
Frontiers in immunology 20180430
Gastrointestinal (GI) parasites, hookworms in particular, have evolved to cause minimal harm to their hosts, allowing them to establish chronic infections. This is mediated by creating an immunoregulatory environment. Indeed, hookworms are such potent suppressors of inflammation that they have been used in clinical trials to treat inflammatory bowel diseases (IBD) and celiac disease. Since the recent description of helminths (worms) secreting extracellular vesicles (EVs), exosome-like EVs from d ...[more]
