Proteomics

Dataset Information

0

Samon_1803_DIA_DDA_HEK - Sensitive quantitative proteomics of human hematopoietic stem and progenitor cells by data-independent acquisition mass spectrometry


ABSTRACT: HEK peptide dilution series acquired in DIA or DDA mode on Orbitrap Lumos

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell

SUBMITTER: Ludovic Gillet  

LAB HEAD: Ruedi Aebersold

PROVIDER: PXD009246 | Pride | 2019-04-25

REPOSITORIES: Pride

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Publications

Sensitive Quantitative Proteomics of Human Hematopoietic Stem and Progenitor Cells by Data-independent Acquisition Mass Spectrometry.

Amon Sabine S   Meier-Abt Fabienne F   Gillet Ludovic C LC   Dimitrieva Slavica S   Theocharides Alexandre P A APA   Manz Markus G MG   Aebersold Ruedi R  

Molecular & cellular proteomics : MCP 20190411 7


Physiological processes in multicellular organisms depend on the function and interactions of specialized cell types operating in context. Some of these cell types are rare and thus obtainable only in minute quantities. For example, tissue-specific stem and progenitor cells are numerically scarce, but functionally highly relevant, and fulfill critical roles in development, tissue maintenance, and disease. Whereas low numbers of cells are routinely analyzed by genomics and transcriptomics, corres  ...[more]

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