Proteomic analysis of E. coli K-12 LE392, P. putida KT2440 under exposure of carbamazepine

ABSTRACT: The goals of this study are to use SWATH-MS to detect bacterial proteomic profiles of wild-type E. coli K-12 LE392, P. putida KT2440, and their quantitative protein response under the exposure of antiepileptic drug carbamazepine. Three concentrations of carbamazepine were applied, which were 0.05 mg/L, 10.0 mg/L and 50.0 mg/L. The group without dosing carbamazepine was the control group. Each concentration was conducted in triplicate. By comparing the proteomic profiles of experimental groups and control group, the effects of carbamazepine on bacterial translational levels can be revealed.

OTHER RELATED OMICS DATASETS IN: GSE112064

INSTRUMENT(S):

ORGANISM(S): Escherichia Coli Pseudomonas Putida Kt2440

TISSUE(S): Cell Culture

SUBMITTER: Jianhua Guo  

LAB HEAD: Jianhua Guo

PROVIDER: PXD009279 | Pride | 2018-10-10

REPOSITORIES: Pride