Proteomics

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Analysis of the temperature-dependent virulence of Pseudomonas plecoglossicida with iTRAQ


ABSTRACT: Pseudomonas plecoglossicida is a facultative pathogen that is associated with diseases of multiple fish, mainly at 15-20 °C. Although fish disease caused by P. plecoglossicida has led to significant economic losses, the mechanisms of the temperature-dependent virulence are unclear. Here, we try to identify potential pathogenicity mechanisms and demonstrate the direct regulation of virulence factors by temperature with iTRAQ.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Pseudomonas Plecoglossicida Nb2011

TISSUE(S): Cell Culture

SUBMITTER: Lixing Huang  

LAB HEAD: Qingpi Yan

PROVIDER: PXD009586 | Pride | 2018-11-22

REPOSITORIES: Pride

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Publications

Integration of Transcriptomic and Proteomic Approaches Reveals the Temperature-Dependent Virulence of <i>Pseudomonas plecoglossicida</i>.

Huang Lixing L   Liu Wenjia W   Jiang Qingling Q   Zuo Yanfei Y   Su Yongquan Y   Zhao Lingmin L   Qin Yingxue Y   Yan Qingpi Q  

Frontiers in cellular and infection microbiology 20180621


<i>Pseudomonas plecoglossicida</i> is a facultative pathogen that is associated with diseases of multiple fish, mainly at 15-20°C. Although fish disease caused by <i>P. plecoglossicida</i> has led to significant economic losses, the mechanisms of the temperature-dependent virulence are unclear. Here, we identify potential pathogenicity mechanisms and demonstrate the direct regulation of several virulence factors by temperature with transcriptomic and proteomic analyses, quantitative real-time PC  ...[more]

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