Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Plasmodium Falciparum Nf54
DISEASE(S): Malaria
SUBMITTER: Kristian Swearingen
LAB HEAD: Robert L. Moritz
PROVIDER: PXD009728 | Pride | 2019-10-02
REPOSITORIES: Pride
Lindner Scott E SE Swearingen Kristian E KE Shears Melanie J MJ Walker Michael P MP Vrana Erin N EN Hart Kevin J KJ Minns Allen M AM Sinnis Photini P Moritz Robert L RL Kappe Stefan H I SHI
Nature communications 20191031 1
Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must navigate the host skin and vasculature to infect the liver. This journey requires distinct proteomes. Here, we report the dynamic transcriptomes and proteomes of both oocyst sporozoites and salivary gland sporozoites in both rodent-infectious Plasmodium yoelii parasites and human-infectious Plasmodium falciparum parasites. The data robustly define mRNAs and proteins that are upregulated in oocyst sporozoites (UO ...[more]