Dataset Information
Proteomic analysis of gamma-tocotienol(GT3)-treated human diploid fibroblasts (HDFs)
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Fibroblast
SUBMITTER: 
Jen-Kit Tan
LAB HEAD: Jen-Kit Tan
PROVIDER: PXD009933 | Pride | 2018-12-06
REPOSITORIES: Pride
Publications
Proteomic profiling of senescent human diploid fibroblasts treated with gamma-tocotrienol.
BMC complementary and alternative medicine 20181129 1
<h4>Background</h4>Replicative senescence of human diploid fibroblasts (HDFs) has been used as a model to study mechanisms of cellular aging. Gamma-tocotrienol (γT3) is one of the members of vitamin E family which has been shown to increase proliferation of senescent HDFs. However, the modulation of protein expressions by γT3 in senescent HDFs remains to be elucidated. Therefore, this study aimed to determine the differentially expressed proteins (DEPs) in young and senescent HDFs; and in vehicl ...[more]
