Acetylation in Borrelia burgdorferi

ABSTRACT: Borelia burgdorferi, the causative agent of the Lyme disease, cycles between a vector (tick) and the mammalian host. Our principal goal is to study how B. burgdorferi adapts its metabolism to colonize and survive in the tick. We established the first growth-phase related acetylome and demonstrated the role of acetylation on central metabolism regulation. We also demonstrated that acetyl phosphate is the primary acetyl donor in B. burgdorferi.

INSTRUMENT(S):

ORGANISM(S): Borrelia Burgdorferi B31

SUBMITTER: Julie Hardouin  

LAB HEAD: Julie Hardouin

PROVIDER: PXD010065 | Pride | 2018-09-24

REPOSITORIES: Pride