Proteomics

Dataset Information

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Environment-driven changes of mRNA and protein levels in Pseudomonas aeruginosa


ABSTRACT: LFQ proteome datasets of Pseudomonas aeruginosa type strain PA14 cultured at different enviromental conditions: Exponential-, transition- and stationary(12 h and 24 h)growth phases. Biofilm (24 h and 48 h), low osmolarity conditions (control = exponential phase), iron starvation and respective control, Sub-MIC ciproflox treatment and respective control.

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Pseudomonas Aeruginosa (strain Ucbpp-pa14)

TISSUE(S): Cell Culture

SUBMITTER: Jelena Erdmann  

LAB HEAD: Andreas Pich

PROVIDER: PXD010200 | Pride | 2018-11-20

REPOSITORIES: Pride

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Publications

Environment-driven changes of mRNA and protein levels in Pseudomonas aeruginosa.

Erdmann Jelena J   Preusse Matthias M   Khaledi Ariane A   Pich Andreas A   Häussler Susanne S  

Environmental microbiology 20181022 11


Systems biology approaches address the challenge of translating sequence information into function. In this study, we described the Pseudomonas aeruginosa PA14 proteomic landscape and quantified environment-driven changes in protein levels by the use of LC-MS techniques. Previously recorded mRNA data allowed a comparison of RNA to protein ratios for each individual gene and, thus, to explore the relationship between an mRNA being differentially expressed between environmental conditions and the  ...[more]

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