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Lung proteome analysis of highly pathogenic avian influenza virus (H5N1) infection progression in chicken

ABSTRACT: This study is planned to characterize the proteome profile of HPAI H5N1 virus infected chicken lung tissues to identify the molecular pathogenesis and proteomic determinant associate with disease progression in susceptible host.

INSTRUMENT(S): Q-Tof ultima

ORGANISM(S): Gallus Gallus (chicken)

TISSUE(S): Lung

DISEASE(S): Avian Influenza

SUBMITTER: Anamika Mishra

LAB HEAD: Anamika Mishra

PROVIDER: PXD010358 | Pride | 2022-03-02

REPOSITORIES: Pride

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Proteomic analysis of differential expression of lung proteins in response to highly pathogenic avian influenza virus infection in chickens.

Vijayakumar Periyasamy P Raut Ashwin Ashok AA Chingtham Santhalembi S Murugkar Harshad V HV Kulkarni Diwakar D DD Sood Richa R Singh Vijendra Pal VP Mishra Anamika A

Archives of virology 20211116 1

Elucidation of the molecular pathogenesis underlying virus-host interactions is important for the development of new diagnostic and therapeutic strategies against highly pathogenic avian influenza (HPAI) virus infection in chickens. However, the pathogenesis of HPAI virus in chickens is not completely understood. To identify the intracellular signaling pathways and critical host proteins associated with influenza pathogenesis, we analyzed the lung proteome of a chicken infected with HPAI H5N1 vi ...[more]

PMID: 34786609

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