Proteomics

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Architecture and structural dynamics of the AROM complex

ABSTRACT: Cross-linking/mass spectrometry was used to study inter-domain interactions in the multifunctional AROM complex from Chaetomium thermophilum.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Chaetomium Thermophilum

SUBMITTER: Alexander Leitner  

LAB HEAD: Alexander Leitner

PROVIDER: PXD010479 | Pride | 2019-10-02

REPOSITORIES: Pride

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With the advance of experimental procedures obtaining chemical crosslinking information is becoming a fast and routine practice. Information on crosslinks can greatly enhance the accuracy of protein structure modeling. Here, we review the current state of the art in modeling protein structures with the assistance of experimentally determined chemical crosslinks within the framework of the 13th meeting of Critical Assessment of Structure Prediction approaches. This largest-to-date blind assessmen  ...[more]

PMID: 31569265

Publication: 1/2

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