Proteomic profiling of sclerosis hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy

ABSTRACT: Proteomics and bioinformatic analyses of hippocampus were performed. High-resolution liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), in combination with TMT-6plex quantification, was applied for global protein expression analysis. The proteomics results were validated by Western blot analysis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain, Neutrophil

DISEASE(S): Temporal Lobe Epilepsy

SUBMITTER: Wei Ge  

LAB HEAD: Wei Ge

PROVIDER: PXD010543 | Pride | 2020-07-17

REPOSITORIES: Pride