Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Monocyte, Cell Culture
SUBMITTER: Joanna Bons
LAB HEAD: Christine Carapito
PROVIDER: PXD010572 | Pride | 2019-05-14
REPOSITORIES: Pride
Molecular & cellular proteomics : MCP 20190315 6
All but thirteen mammalian mitochondrial proteins are encoded by the nuclear genome, translated in the cytosol and then imported into the mitochondria. For a significant proportion of the mitochondrial proteins, import is coupled with the cleavage of a presequence called the transit peptide, and the formation of a new N-terminus. Determination of the neo N-termini has been investigated by proteomic approaches in several systems, but generally in a static way to compile as many N-termini as possi ...[more]