Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture, Fibroblast
SUBMITTER: Sebastian Wiese
LAB HEAD: Sebastian Wiese
PROVIDER: PXD010773 | Pride | 2019-11-12
REPOSITORIES: Pride
Hecht Matthias M Rösler Reinhild R Wiese Sebastian S Johnsson Nils N Gronemeyer Thomas T
G3 (Bethesda, Md.) 20190605 6
Septins regulate the organization of the actin cytoskeleton, vesicle transport and fusion, chromosome alignment and segregation, and cytokinesis in mammalian cells. SEPT9 is part of the core septin hetero-octamer in human cells which is composed of SEPT2, SEPT6, SEPT7, and SEPT9. SEPT9 has been linked to a variety of intracellular functions as well as to diseases and diverse types of cancer. A targeted high-throughput approach to systematically identify the interaction partners of SEPT9 has not ...[more]