Proteome evolution under essential resource limitation

ABSTRACT: Resource limitation is a major driver of ecological and evolutionary dynamics of organisms. Short-term responses to resource limitation include plastic changes in molecular phenotypes including protein expression. Yet little is known about the evolution of the molecular phenotype under longer-term resource limitation. Here, we combine experimental evolution of the green alga Chlamydomonas reinhardtii under multiple different non-substitutable resource limitation regimes with proteomic measurements to investigate evolutionary adaptation of the molecular phenotype. We demonstrate convergent proteomic evolution of core metabolic functions, including the Calvin-Benson cycle and gluconeogenesis, across different resource limitation selection environments. We did not observe proteomic changes consistent with optimized uptake of the different particular limiting resources.

INSTRUMENT(S):

ORGANISM(S): Chlamydomonas Reinhardtii

TISSUE(S): Plant Cell, Photosynthetic Cell

SUBMITTER: Alexander Betz  

LAB HEAD: Anita Julianne Tricia Narwani

PROVIDER: PXD010847 | Pride | 2018-11-08

REPOSITORIES: pride