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Cross-linking/mass spectrometry for the 13th Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP13)

ABSTRACT: High-density cross-linking/mass spectrometry data was provided for four targets (T0957, T0968, T0975 and T0987) in the CASP13 experiment (https://www.predictioncenter.org/casp13/index.cgi).

INSTRUMENT(S): LTQ Orbitrap

ORGANISM(S): Enterococcus Faecalis (streptococcus Faecalis) Homo Sapiens (human) Escherichia Coli Klebsiella Pneumoniae 342

SUBMITTER: Adam Belsom

LAB HEAD: Juri Rappsilber

PROVIDER: PXD010884 | Pride | 2019-10-07

REPOSITORIES: Pride

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Assessment of chemical-crosslink-assisted protein structure modeling in CASP13.

Fajardo J Eduardo JE Shrestha Rojan R Gil Nelson N Belsom Adam A Crivelli Silvia N SN Czaplewski Cezary C Fidelis Krzysztof K Grudinin Sergei S Karasikov Mikhail M Karczyńska Agnieszka S AS Kryshtafovych Andriy A Leitner Alexander A Liwo Adam A Lubecka Emilia A EA Monastyrskyy Bohdan B Pagès Guillaume G Rappsilber Juri J Sieradzan Adam K AK Sikorska Celina C Trabjerg Esben E Fiser Andras A

Proteins 20191007 12

With the advance of experimental procedures obtaining chemical crosslinking information is becoming a fast and routine practice. Information on crosslinks can greatly enhance the accuracy of protein structure modeling. Here, we review the current state of the art in modeling protein structures with the assistance of experimentally determined chemical crosslinks within the framework of the 13th meeting of Critical Assessment of Structure Prediction approaches. This largest-to-date blind assessmen ...[more]

PMID: 31569265

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