Proteomics

Dataset Information

0

PAXX and its paralogues synergistically direct DNA polymerase I activity in DNA repair


ABSTRACT: In this study, we characterised the interactomes of PAXX and its paralogs, XLF and XRCC4, to show that these factors share the ability to interact with DNA polymerase lambda (Poll), stimulate its activityand are required for the recruitment of Poll to laser-induced DNA damage sites.

INSTRUMENT(S): Synapt MS

ORGANISM(S): Homo Sapiens (human)

DISEASE(S): Dna

SUBMITTER: Rebekah Jukes-Jones  

LAB HEAD: Michal Malewicz

PROVIDER: PXD010891 | Pride | 2018-09-24

REPOSITORIES: Pride

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