PAXX and its paralogues synergistically direct DNA polymerase I activity in DNA repair
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ABSTRACT: In this study, we characterised the interactomes of PAXX and its paralogs, XLF and XRCC4, to show that these factors share the ability to interact with DNA polymerase lambda (Poll), stimulate its activityand are required for the recruitment of Poll to laser-induced DNA damage sites.
INSTRUMENT(S): Synapt MS
ORGANISM(S): Homo Sapiens (human)
DISEASE(S): Dna
SUBMITTER: Rebekah Jukes-Jones
LAB HEAD: Michal Malewicz
PROVIDER: PXD010891 | Pride | 2018-09-24
REPOSITORIES: Pride
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