Dataset Information
Building comprehensive MS-friendly databases for proteomic analysis of bacterial species of unknown genetic background
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Mycobacterium Tuberculosis
SUBMITTER: 
Gustavo De Souza
LAB HEAD: Gustavo de Souza
PROVIDER: PXD011080 | Pride | 2019-11-12
REPOSITORIES: Pride
Publications
On the Impact of the Pangenome and Annotation Discrepancies While Building Protein Sequence Databases for Bacteria Proteogenomics.
Frontiers in microbiology 20190620
In proteomics, peptide information within mass spectrometry (MS) data from a specific organism sample is routinely matched against a protein sequence database that best represent such organism. However, if the species/strain in the sample is unknown or genetically poorly characterized, it becomes challenging to determine a database which can represent such sample. Building customized protein sequence databases merging multiple strains for a given species has become a strategy to overcome such re ...[more]
