Dataset Information
Mucolytic activity of Akkermansia muciniphila enables Human Milk Oligosaccharides degradation.
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Akkermansia Muciniphila Atcc Baa-835
SUBMITTER: 
Sjef Boeren
LAB HEAD: Sjef Boeren
PROVIDER: PXD011357 | Pride | 2020-09-07
REPOSITORIES: Pride
Publications
Akkermansia muciniphila uses human milk oligosaccharides to thrive in the early life conditions in vitro.
Scientific reports 20200831 1
Akkermansia muciniphila is a well-studied anaerobic bacterium specialized in mucus degradation and associated with human health. Because of the structural resemblance of mucus glycans and free human milk oligosaccharides (HMOs), we studied the ability of A. muciniphila to utilize human milk oligosaccharides. We found that A. muciniphila was able to grow on human milk and degrade HMOs. Analyses of the proteome of A. muciniphila indicated that key-glycan degrading enzymes were expressed when the b ...[more]
