EspB deletion mutant of Mycobacterium tuberculosis

ABSTRACT: The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we investigate the effect of espB on the secretion of ESX-1 components and other proetins, as well as virulence.

INSTRUMENT(S):

ORGANISM(S): Mycobacterium Tuberculosis H37rv

TISSUE(S): Cell Culture, Cell Line Cell

DISEASE(S): Pulmonary Tuberculosis

SUBMITTER: Andrej Benjak  

LAB HEAD: Stewart Thomas Cole

PROVIDER: PXD011475 | Pride | 2021-09-24

REPOSITORIES: Pride