Proteomic And Phosphoproteomic Study Of Placenta And Fetal Liver In Mice With Diet-Induced Obesity

ABSTRACT: Maternal obesity in mice negatively affects placental functionand maternal and fetal liver function. We performed a global proteomic analysis using a liquid-chromatography/mass-spectrometry system to investigate total and phosphorylated proteins in the placenta and fetal liver in a mouse model that combines maternal obesity with maternal androgen excess to identify changes in molecular pathways that might promote diseases in adulthood.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Placenta, Liver

DISEASE(S): Obesity

SUBMITTER: Egor Vorontsov  

LAB HEAD: Elisabet Stener-Victorin

PROVIDER: PXD011722 | Pride | 2019-01-24

REPOSITORIES: Pride