Proteomics

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Proteomic analysis of multiple pig tissues reveals hundreds of Toxoplasma gondii responsive proteins that could participate in Toxoplasma gondii control in vivo


ABSTRACT: Proteomic analysis of multiple pig tissues reveals hundreds of Toxoplasma gondii responsive proteins that could participate in Toxoplasma gondii control in vivo

INSTRUMENT(S): TripleTOF 5600

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Liver

SUBMITTER: he junjun  

LAB HEAD: Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences (LVRI, CAAS)

PROVIDER: PXD011816 | Pride | 2020-05-26

REPOSITORIES: Pride

Dataset's files

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Publications

iTRAQ-based Quantitative Proteomics Analysis Identifies Host Pathways Modulated during <i>Toxoplasma gondii</i> Infection in Swine.

He Jun-Jun JJ   Ma Jun J   Wang Jin-Lei JL   Zhang Fu-Kai FK   Li Jie-Xi JX   Zhai Bin-Tao BT   Elsheikha Hany M HM   Zhu Xing-Quan XQ  

Microorganisms 20200405 4


<i>Toxoplasma gondii</i> is a leading cause of foodborne illness and consumption of undercooked pig meat is a major risk factor for acquiring toxoplasmosis, which causes a substantial burden on society. Here, we used isobaric tags for relative and absolute quantification (iTRAQ) labelling coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify cellular proteins and pathways altered during <i>T. gondii</i> infection in pigs. We also used parallel reaction monitoring-bas  ...[more]

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