Ventriculomics analyses of autopsy AD tissue
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain
DISEASE(S): Alzheimer's Disease
SUBMITTER: 
Joseph Ojo
LAB HEAD: Joseph Ojo
PROVIDER: PXD012059 | Pride | 2021-09-08
REPOSITORIES: Pride
Publications
Molecular abnormalities in autopsied brain tissue from the inferior horn of the lateral ventricles of nonagenarians and Alzheimer disease patients.
Pearson Andrew A Ajoy Rosa R Crynen Gogce G Reed Jon M JM Algamal Moustafa M Mullan Michael M Purohit Dushyant D Crawford Fiona F Ojo Joseph O JO
BMC neurology 20200827 1
<h4>Background</h4>The ventricular system plays a vital role in blood-cerebrospinal fluid (CSF) exchange and interstitial fluid-CSF drainage pathways. CSF is formed in the specialized secretory tissue called the choroid plexus, which consists of epithelial cells, fenestrated capillaries and the highly vascularized stroma. Very little is currently known about the role played by the ventricles and the choroid plexus tissue in aging and Alzheimer's disease (AD).<h4>Methods</h4>In this study, we use ...[more]
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