Proteomic Profiling of Mammalian COPII Vesicles

ABSTRACT: By combining in vitro COPII vesicle reconstitutions and SILAC-based mass spectrometric analysis this study aims to identify the core proteome of mammalian COPII vesicles. Furthermore proteomes generated from vesicles with different Sec24 isoforms have been investigated with the same approach to identify isoform-dependent cargo proteins.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Bernd Hessling  

LAB HEAD: Felix T Wieland

PROVIDER: PXD012128 | Pride | 2019-01-07

REPOSITORIES: Pride