Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain
SUBMITTER: Justin McKetney
LAB HEAD: Joshua J Coon
PROVIDER: PXD012131 | Pride | 2020-01-09
REPOSITORIES: Pride
McKetney Justin J Runde Rosalyn M RM Hebert Alexander S AS Salamat Shahriar S Roy Subhojit S Coon Joshua J JJ
Journal of proteome research 20190220 3
The brain represents one of the most divergent and critical organs in the human body. Yet, it can be afflicted by a variety of neurodegenerative diseases specifically linked to aging, about which we lack a full biomolecular understanding of onset and progression, such as Alzheimer's disease (AD). Here we provide a proteomic resource comprising nine anatomically distinct sections from three aged individuals, across a spectrum of disease progression, categorized by quantity of neurofibrillary tang ...[more]