Proteomics

Dataset Information

0

Proteomic analyses of Mycobacterium tuberculosis associated sputum and plasma


ABSTRACT: Tuberculosis (TB) remains one of the world’s major infectious diseases affecting nations with limited public health resources. Multidrug resistance development has seriously compromised therapeutic treatment choices. The pathology of latent TB shows evidence of a reservoir of Mycobacterium tuberculosis (Mtb) in the lungs of affected individuals. If the pathogen is contained by the immune system, no overt disease symptoms occur. The environmental and internal triggers leading to disease reactivation are not well understood. Proteomic investigations of blood plasma and sputum derived from subjects with active TB versus latent TB versus healthy individuals may yield new biomarkers and, when surveying larger longitudinally monitored cohorts, may discriminate infection outcomes in an endemic setting.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human) Mycobacterium Tuberculosis

TISSUE(S): Blood Plasma, Sputum

SUBMITTER: Yanbao Yu  

LAB HEAD: Yanbao Yu

PROVIDER: PXD012412 | Pride | 2021-05-26

REPOSITORIES: Pride

Similar Datasets

2021-05-11 | GSE161829 | GEO
2010-11-18 | GSE25435 | GEO
2023-01-03 | GSE185372 | GEO
2009-05-07 | GSE15977 | GEO
| E-GEOD-15977 | biostudies-arrayexpress
| E-GEOD-25435 | biostudies-arrayexpress
| E-GEOD-27984 | biostudies-arrayexpress
2018-06-14 | GSE99373 | GEO
2019-06-12 | GSE84445 | GEO
2020-05-26 | GSE99374 | GEO