Proteomics

Dataset Information

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Francisella noatunensis subsp orientalis FNO12 pseudogene validation


ABSTRACT: Due to the detection of mRNA expression for several protein CDS annotated as pseudogenes in the results of the microarray experiment, a shotgun proteomic approach was applied to verify actual protein translation for each pseudogene in the genome of FNO12.

INSTRUMENT(S): Synapt MS

ORGANISM(S): Francisella Noatunensis Subsp. Orientalis Fno12

TISSUE(S): Cell Culture

SUBMITTER: Henrique César Pereira Figueiredo  

LAB HEAD: Henrique César Pereira Figueiredo

PROVIDER: PXD012449 | Pride | 2019-05-27

REPOSITORIES: Pride

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Publications

Effects of temperature changes in the transcriptional profile of the emerging fish pathogen Francisella noatunensis subsp. orientalis.

Pereira Felipe Luiz FL   Tavares Guilherme Campos GC   de Carvalho Alex Fiorini AF   Rosa Júlio César Camara JCC   Rezende Cristiana Perdigão CP   Leal Carlos Augusto Gomes CAG   Figueiredo Henrique César Pereira HCP  

Microbial pathogenesis 20190518


One of the major challenges in Nile tilapia (Oreochromis niloticus L.) farming is the occurrence of bacterial infections, and the Francisella noatunensis subsp. orientalis (FNO) is an important pathogen that has emerged in last decades. Francisellosis outbreaks have been reported in the literature as occurring seasonally when water temperature is below 24 °C. The aim of this study was to quantify the median lethal doses (LD<sub>50</sub>) of FNO in experimental challenges at 28 °C and 22 °C, and  ...[more]

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