Proteomic analyses of urine for healty ageing study
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Urine
SUBMITTER: 
Yanbao Yu
LAB HEAD: Yanbao Yu
PROVIDER: PXD012477 | Pride | 2021-09-08
REPOSITORIES: Pride
Publications
Protein signatures from blood plasma and urine suggest changes in vascular function and IL-12 signaling in elderly with a history of chronic diseases compared with an age-matched healthy cohort.
Yu Yanbao Y Singh Harinder H Kwon Keehwan K Tsitrin Tamara T Petrini Joann J Nelson Karen E KE Pieper Rembert R
GeroScience 20200924 2
Key processes characterizing human aging are immunosenescence and inflammaging. The capacity of the immune system to adequately respond to external perturbations (e.g., pathogens, injuries, and biochemical irritants) and to repair somatic mutations that may cause cancers or cellular senescence declines. An important goal remains to identify genetic or biochemical, predictive biomarkers for healthy aging. We recruited two cohorts in the age range 70 to 82, one afflicted by chronic illnesses (non- ...[more]
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