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Nematostella life stages LC-msms

ABSTRACT: Nematostella vectensis is a venomous organism with a complex life cycle. This dataset is to complement the dataset PXD008218 where proteoms of several Nematostella life stages (unfertilised eggs, planulae, primary polyp, adult male and female) were analyzed to compare toxins abbunances. Here we re-ran unfertilized eggs LC-MSMS (4 replicates) separately from other life stages to eliminate cross-contamination with abbundant toxins expressed at adult stage. To control for comparability to the older PXD008218 dataset we also re-ran adult female LC-MSMS (1 replicate). Same samples as inPXD008218 were used.

INSTRUMENT(S):

ORGANISM(S): Nematostella Vectensis

TISSUE(S): Whole Body, Oocyte

SUBMITTER: Maria Sachkova

LAB HEAD: Yehu Moran

PROVIDER: PXD012719 | Pride | 2026-03-09

REPOSITORIES: Pride

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	Search_files.zip	Other
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Publications

The Birth and Death of Toxins with Distinct Functions: A Case Study in the Sea Anemone Nematostella.

Sachkova Maria Y MY Singer Shir A SA Macrander Jason J Reitzel Adam M AM Peigneur Steve S Tytgat Jan J Moran Yehu Y

Molecular biology and evolution 20190901 9

The cnidarian Nematostella vectensis has become an established lab model, providing unique opportunities for venom evolution research. The Nematostella venom system is multimodal: involving both nematocytes and ectodermal gland cells, which produce a toxin mixture whose composition changes throughout the life cycle. Additionally, their modes of interaction with predators and prey vary between eggs, larvae, and adults, which is likely shaped by the dynamics of the venom system. Nv1 is a major com ...[more]

PMID: 31134275

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