Developing In Vivo Cross-linking Mass Spectrometry (XL-MS) to Decipher Protein Interaction Landscapes at the Proteome Scale
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ABSTRACT: We have developed a new and robust in vivo cross-linking mass spectrometry (XL-MS) that utilizes a multifunctional MS-cleavable cross-linker to enable the efficient capture, enrichment, and identification of in vivo cross-linked peptides at the whole proteome scale.
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Embryonic Cell
SUBMITTER: Andrew Wheat
LAB HEAD: Lan Huang
PROVIDER: PXD012788 | Pride | 2021-07-30
REPOSITORIES: Pride
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