Ontology highlight
ABSTRACT:
INSTRUMENT(S): maXis
ORGANISM(S): Conus Monile
TISSUE(S): Venom Duct, Epithelial Cell
SUBMITTER: P Balaram
LAB HEAD: Prof.P.Balaram, Molecular Biophysics Unit
PROVIDER: PXD012899 | Pride | 2020-02-21
REPOSITORIES: Pride
Biochimica et biophysica acta. Proteins and proteomics 20200210 5
Transcriptomic analysis of cone snail venom duct tissue has permitted the identification of diverse conopressin/conophysin precursor sequences from seven distinct Conus species. Multiple precursor isoforms are present in C.monile, C.lividus and C.loroisii. Aqueous extracts of the venom duct tissue from C.monile yield a band, at ~ 15-20 kDa on SDS-PAGE. In-gel trypsin digestion, followed by mass spectrometry establishes the presence of two distinct conopressin/conophysin isoforms that differ at p ...[more]