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Mass spectrometry data of human urine

ABSTRACT: Based on UPLC-Q-TOF-MS metabolomics technology, urine samples of 1072 subjects from 9 centers, including normal control, phlegm and blood stasis (PBS) syndrome and Qi and Yin deficiency (QYD) syndrome, and other syndromes of CHD, were conducted to find biomarkers. Among them, the discovery set (n = 125) and the test set (n = 337) were used to identify and validate biomarkers, and the validation set (n = 610) was used for the application and evaluation of the support vector machine (SVM) prediction model.

INSTRUMENT(S): Q-Tof ultima

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Urine

SUBMITTER: Yubo Li

LAB HEAD: Yubo Li

PROVIDER: PXD012910 | Pride | 2019-03-27

REPOSITORIES: Pride

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A Large-Scale, Multi-Center Urine Biomarkers Identification of Coronary Heart Disease in TCM Syndrome Differentiation.

Zhou Haonan H Li Lin L Zhao Huan H Wang Yuming Y Du Jun J Zhang Pengjie P Li Chunjie C Wang Xianliang X Liu Yuechen Y Xu Qiang Q Zhang Tianpu T Song Yanqi Y Yu Chunquan C Li Yubo Y

Journal of proteome research 20190409 5

Coronary heart disease (CHD) threatens human health. The discovery and assessment of potential biometabolic markers for different syndrome types of CHD may contribute to decipher pathophysiological mechanisms and identify new targets for diagnosis and treatment. On the basis of UPLC-Q-TOF/MS metabolomics technology, urine samples of 1072 participants from nine centers, including normal control, phlegm and blood stasis (PBS) syndrome and Qi and Yin deficiency (QYD) syndrome, and other syndromes o ...[more]

PMID: 30907085

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