Proteomics

Dataset Information

0

Secretome of Granulicatella adiacens


ABSTRACT: This project investigated the proteins secreted into extracellular medium by the oral bacterium G. adiacens.

INSTRUMENT(S): LTQ FT

ORGANISM(S): Granulicatella Adiacens Atcc 49175

SUBMITTER: Maribasappa Karched  

LAB HEAD: Maribasappa Karched

PROVIDER: PXD013000 | Pride | 2019-04-09

REPOSITORIES: Pride

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Publications

Proteomic Analysis and Virulence Assessment of <i>Granulicatella adiacens</i> Secretome.

Karched Maribasappa M   Bhardwaj Radhika G RG   Tiss Ali A   Asikainen Sirkka S  

Frontiers in cellular and infection microbiology 20190424


Despite reports on the occurrence of <i>Granulicatella adiacens</i> in infective endocarditis, few mechanistic studies on its virulence characteristics or pathogenicity are available. Proteins secreted by this species may act as determinants of host-microbe interaction and play a role in virulence. Our aim in this study was to investigate and functionally characterize the secretome of <i>G. adiacens</i>. Proteins in the secretome preparation were digested by trypsin and applied to nanoLC-ESI-MS/  ...[more]

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